GRB10 Antikörper (AA 1-100)

Produktnummer ABIN5663731

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GRB10 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GRB10 Antikörper (AA 1-100) (ABIN5663731)

Target: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRB10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRB10 Antikörper

Bindungsspezifität: AA 1-100

Sequenz: MALAGCPDSF LHHPYYQDKV EQTPRSQQDP AGPGLPAQSD RLANHQEDDV DLEALVNDMN ASLESLYSAC SMQSDTVPLL QNGQHARSQP RASGPPRSIQ

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GRB10 (NP_005302.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GRB10

Target: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Andere Bezeichnung: GRB10

Hintergrund: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.,GRB10,GRB-IR,Grb-10,IRBP,MEG1,RSS,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,GRB10

Molekulargewicht: 60 kDa/62 kDa/66 kDa/67 kDa

Gen-ID: 2887

UniProt: Q13322

Pathways: Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2