GATA3 Antikörper (AA 1-197) (Fluoro647)
Kurzübersicht für GATA3 Antikörper (AA 1-197) (Fluoro647) (ABIN7992947)
Target
Alle GATA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-197
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Verwendungszweck
- Anti-GATA3 Antibody Fluoro647 Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Homologie
- Human GATA3 shares 95% amino acid (aa) sequence identity with mouse GATA3.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human GATA3 recombinant protein (Position: M1-E197). Human GATA3 shares 95% amino acid (aa) sequence identity with mouse GATA3.
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- GATA3 (GATA Binding Protein 3 (GATA3))
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Andere Bezeichnung
- GATA3
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Hintergrund
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Background: Trans-acting T-cell-specific transcription factor GATA-3, also named HDR or GATA3, is a protein that in humans is encoded by the GATA3 gene. It is mapped to 10p14. This gene belongs to the GATA family of transcription factors. It regulates luminal epithelial cell differentiation in the mammary gland. The protein contains two GATA-type zinc fingers, it is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells, and induces the differentiation of Th0 cells towards this T cell subtype while suppressing their differentiation towards Th1 cells.
Gene Full Name: GATA binding protein 3
Sequence Similarities: Contains 2 GATA-type zinc fingers.
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Gen-ID
- 2625
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UniProt
- P23771
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Pathways
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
Target
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