GATA3 Antikörper

Produktnummer ABIN969168

Produktdetails anti-GATA3 Antikörper

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GATA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human GATA3 expressed in E. coli.

Klon: 7B5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-GATA3 Antikörper (ABIN969168)

Muzzioli, Stecconi, Moresi, Provinciali: "Zinc improves the development of human CD34+ cell progenitors towards NK cells and increases the expression of GATA-3 transcription factor in young and old ages." in: Biogerontology, Vol. 10, Issue 5, pp. 593-604, (2009) (PubMed).

van Hamburg, Mus, de Bruijn, de Vogel, Boon, Cornelissen, Asmawidjaja, Hendriks, Lubberts: "GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis." in: Arthritis and rheumatism, Vol. 60, Issue 3, pp. 750-9, (2009) (PubMed).

Details zu GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Andere Bezeichnung: GATA3 (GATA3 Produkte)

Synonyme: HDR antikoerper, HDRS antikoerper, Gata-3 antikoerper, jal antikoerper, cb550 antikoerper, gta3 antikoerper, GATA-3 antikoerper, XGATA3 antikoerper, xgata-3 antikoerper, hdr antikoerper, xGATA-3 antikoerper, GATA3 antikoerper, GATA transcription factor 3 antikoerper, T4L20.260 antikoerper, T4L20_260 antikoerper, gata3 antikoerper, ZH-DR antikoerper, zgc:103531 antikoerper, GATA binding protein 3 antikoerper, GATA binding protein 3 S homeolog antikoerper, GATA transcription factor 3 antikoerper, amidase antikoerper, putative amidase antikoerper, GATA-binding protein 3 antikoerper, hematopoietic death receptor antikoerper, GATA3 antikoerper, Gata3 antikoerper, gata3 antikoerper, gata3.S antikoerper, gatA3 antikoerper, hdr antikoerper

Hintergrund:

Description: This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. (provided by RefSeq) Tissue specificity: T-cells and endothelial cells RD: GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.

Aliases: HDR,MGC2346,MGC5199,MGC5445,GATA3

Molekulargewicht: 48 kDa

Gen-ID: 2625

HGNC: 2625

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation