FGF3 Antikörper (AA 18-239) (Biotin)

Produktnummer ABIN7990609

Der Kaninchen Polyklonal anti-FGF3 Antikörper wird verwendet zum Nachweis von FGF3 in Proben von Human. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für FGF3 Antikörper (AA 18-239) (Biotin) (ABIN7990609)

Target: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF3 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-FGF3 Antikörper (Biotin)

Bindungsspezifität: AA 18-239

Verwendungszweck: Anti-FGF3 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FGF3 recombinant protein (Position: A18-H239).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FGF3

Target: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Andere Bezeichnung: FGF3

Hintergrund:

Background: INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.

Gene Full Name: fibroblast growth factor 3

Gen-ID: 2248

UniProt: P11487

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung