FGF23 Antikörper (AA 48-251)

Produktnummer ABIN7990597

Der Kaninchen Polyklonal anti-FGF23 Antikörper wird verwendet zum Nachweis von FGF23 in Proben von Maus. Er wurde validiert für WB.

Kurzübersicht für FGF23 Antikörper (AA 48-251) (ABIN7990597)

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Güteklasse: Carrier-free

Produktdetails anti-FGF23 Antikörper

Bindungsspezifität: AA 48-251

Verwendungszweck: Anti-FGF23 Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: coli-derived mouse FGF23 recombinant protein (Position: R48-V251). Mouse FGF23 shares 71.1%,94.6% amino acid (aa) sequence identity with human,rat FGF23,respectively.

Produktmerkmale: Anti-FGF23 Antibody. Tested in WB applications. This antibody reacts with Mouse.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse FGF23 recombinant protein (Position: R48-V251). Mouse FGF23 shares 71.1% and 94.6% amino acid (aa) sequence identity with human and rat FGF23, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Andere Bezeichnung: Fgf23

Hintergrund:

Background: Fibroblast growth factor 23?or?FGF23?is a?protein?that in humans is encoded by the?FGF23?gene. This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

Gene Full Name: fibroblast growth factor 23

Molekulargewicht: 34 kDa

Gen-ID: 64654

UniProt: Q9EPC2

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion