FGF23 Antikörper (AA 48-251) (PE)

Produktnummer ABIN7990595

Der PE-konjugierte Kaninchen Polyklonal anti-FGF23 Antikörper (ABIN7990595) detektiert spezifisch FGF23 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für FGF23 Antikörper (AA 48-251) (PE) (ABIN7990595)

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF23 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-FGF23 Antikörper (PE)

Bindungsspezifität: AA 48-251

Verwendungszweck: Anti-FGF23 Antibody PE Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: coli-derived mouse FGF23 recombinant protein (Position: R48-V251). Mouse FGF23 shares 71.1%,94.6% amino acid (aa) sequence identity with human,rat FGF23,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse FGF23 recombinant protein (Position: R48-V251). Mouse FGF23 shares 71.1% and 94.6% amino acid (aa) sequence identity with human and rat FGF23, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Andere Bezeichnung: Fgf23

Hintergrund:

Background: Fibroblast growth factor 23?or?FGF23?is a?protein?that in humans is encoded by the?FGF23?gene. This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

Gene Full Name: fibroblast growth factor 23

Gen-ID: 64654

UniProt: Q9EPC2

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion