Fibrillarin Antikörper (AA 77-138) (Fluoro594)

Produktnummer ABIN7990283

Der Fluoro594-konjugierte Kaninchen Polyklonal anti-Fibrillarin Antikörper (ABIN7990283) detektiert spezifisch Fibrillarin in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Affe.

Kurzübersicht für Fibrillarin Antikörper (AA 77-138) (Fluoro594) (ABIN7990283)

Target: Fibrillarin (FBL)

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibrillarin Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Fibrillarin Antikörper (Fluoro594)

Bindungsspezifität: AA 77-138

Verwendungszweck: Anti-Fibrillarin/FBL Antibody Fluoro594 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Fibrillarin/FBL recombinant protein (Position: K77-N138).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Fibrillarin

Target: Fibrillarin (FBL)

Andere Bezeichnung: FBL

Hintergrund:

Background: rRNA 2'-O-methyltransferase fibrillarin is an enzyme that in humans is encoded by the FBL gene. This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.

Gene Full Name: fibrillarin rRNA 2'-O-methyltransferase

Gen-ID: 2091

UniProt: P22087

Pathways: Ribonucleoside Biosynthetic Process