F11R Antikörper (N-Term) (FITC)

Produktnummer ABIN7989502

Der Kaninchen Polyklonal anti-F11R Antikörper wird verwendet zum Nachweis von F11R in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für F11R Antikörper (N-Term) (FITC) (ABIN7989502)

Target: F11R (F11 Receptor (F11R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F11R Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-F11R Antikörper (FITC)

Bindungsspezifität: N-Term

Verwendungszweck: Anti-JAM-A/F11R Antibody FITC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human JAM-A/F11R, which shares 75% and 80% amino acid (aa) sequence identity with mouse and rat JAM-A/F11R, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu F11R

Target: F11R (F11 Receptor (F11R))

Andere Bezeichnung: F11R

Hintergrund:

Background: Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Gene Full Name: F11 receptor

Gen-ID: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization