XPO1 Antikörper (AA 966-1071) (Fluoro594)
Kurzübersicht für XPO1 Antikörper (AA 966-1071) (Fluoro594) (ABIN7989368)
Target
Alle XPO1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 966-1071
-
Verwendungszweck
- Anti-CRM1/XPO1 Antibody Fluoro594 Conjugated
-
Spezifität
- No cross reactivity with other proteins.
-
Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
-
Homologie
- Human CRM1 shares 93.4%,91.5% amino acid (aa) sequence identity with mouse,rat CRM1,respectively.
-
Aufreinigung
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human CRM1 recombinant protein (Position: N966-D1071). Human CRM1 shares 93.4% and 91.5% amino acid (aa) sequence identity with mouse and rat CRM1, respectively.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
Haltbarkeit
- 12 months
-
-
- XPO1 (Exportin 1 (XPO1))
-
Andere Bezeichnung
- XPO1
-
Hintergrund
-
Background: Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mapped to human chromosome 2p16 by fluorescence in situ hybridization. This protein mediates leucine-rich nuclear export signal (NES)-dependent protein transport. It specifically inhibits the nuclear export of Rev and U snRNAs. Additionally, this protein is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. It also regulates NFAT and AP-1.
Gene Full Name: exportin 1
-
Gen-ID
- 7514
-
UniProt
- O14980
-
Pathways
- M Phase
Target
-