ERN2 Antikörper (AA 517-919)

Produktnummer ABIN7987663

Der Kaninchen Polyklonal anti-ERN2 Antikörper wird verwendet zum Nachweis von ERN2 in Proben von Human. Er wurde validiert für ELISA, WB und FACS.

Kurzübersicht für ERN2 Antikörper (AA 517-919) (ABIN7987663)

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERN2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-ERN2 Antikörper

Bindungsspezifität: AA 517-919

Verwendungszweck: Anti-ERN2 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-ERN2 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ERN2 recombinant protein (Position: K517-P919).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ERN2

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Andere Bezeichnung: ERN2

Hintergrund:

Background: ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.

Gene Full Name: endoplasmic reticulum to nucleus signaling 2

Molekulargewicht: 102 kDa

Gen-ID: 10595

UniProt: Q76MJ5