ERN2 Antikörper (AA 517-919) (Fluoro488)
Kurzübersicht für ERN2 Antikörper (AA 517-919) (Fluoro488) (ABIN7987655)
Target
Alle ERN2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 517-919
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Verwendungszweck
- Anti-ERN2 Antibody Fluoro488 Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human ERN2 recombinant protein (Position: K517-P919).
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
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Andere Bezeichnung
- ERN2
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Hintergrund
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Background: ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
Gene Full Name: endoplasmic reticulum to nucleus signaling 2
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Gen-ID
- 10595
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UniProt
- Q76MJ5
Target
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