ERN2 Antikörper (AA 517-919) (Biotin)

Produktnummer ABIN7987653

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ERN2 in ELISA, WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ERN2 Antikörper (AA 517-919) (Biotin) (ABIN7987653)

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERN2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ERN2 Antikörper (Biotin)

Bindungsspezifität: AA 517-919

Verwendungszweck: Anti-ERN2 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ERN2 recombinant protein (Position: K517-P919).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ERN2

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Andere Bezeichnung: ERN2

Hintergrund:

Background: ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.

Gene Full Name: endoplasmic reticulum to nucleus signaling 2

Gen-ID: 10595

UniProt: Q76MJ5