Dystrophin Antikörper (AA 3076-3404) (HRP)

Produktnummer ABIN7986729

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Dystrophin in IHC, WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Dystrophin Antikörper (AA 3076-3404) (HRP) (ABIN7986729)

Target: Dystrophin (DMD)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dystrophin Antikörper ist konjugiert mit HRP

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Produktdetails anti-Dystrophin Antikörper (HRP)

Bindungsspezifität: AA 3076-3404

Verwendungszweck: Anti-Dystrophin/DMD Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Dystrophin shares 100% amino acid (aa) sequence identity with mouse Dystrophin.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Dystrophin recombinant protein (Position: H3076-D3404). Human Dystrophin shares 100% amino acid (aa) sequence identity with mouse Dystrophin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Dystrophin

Target: Dystrophin (DMD)

Andere Bezeichnung: DMD

Hintergrund:

Background: Dystrophin, also known as DMD, is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. It is mapped to Xp21.2-p21.1. This complex is variously known as the costamere or thedystrophin-associated protein complex. Many muscle proteins, such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. Dystrophin is a protein located between the sarcolemma and the outermost layer of myofilaments in the muscle fiber (myofiber). It is a cohesive protein, linking actin filaments to another support protein that resides on the inside surface of each muscle fiber's plasma membrane (sarcolemma).

Gene Full Name: dystrophin

Sequence Similarities: Contains 2 CH (calponin-homology) domains.

Gen-ID: 1756

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development