SPTAN1 Antikörper (AA 551-650) (FITC)

Produktnummer ABIN748950

Produktdetails anti-SPTAN1 Antikörper (FITC)

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Bindungsspezifität: AA 551-650

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTAN1 Antikörper ist konjugiert mit FITC

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPECA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Andere Bezeichnung: SPECA (SPTAN1 Produkte)

Synonyme: im:7157190 antikoerper, wu:fa20e05 antikoerper, wu:fb33g08 antikoerper, wu:fk32a10 antikoerper, zgc:112229 antikoerper, 2610027H02Rik antikoerper, Spna-2 antikoerper, Spna2 antikoerper, EIEE5 antikoerper, NEAS antikoerper, SPTA2 antikoerper, A2a antikoerper, IPF antikoerper, SPECA antikoerper, spectrin alpha, non-erythrocytic 1 antikoerper, spectrin, alpha, non-erythrocytic 1 antikoerper, SPTAN1 antikoerper, sptan1 antikoerper, Sptan1 antikoerper

Hintergrund:

Synonyms: Fodrin alpha chain, ALPHAII-SPECTRIN, Alpha II Spectrin, FLJ44613, Fodrin, alpha, NEAS, Non erythrocytic spectrin alpha, SPECA, Spectrin alpha chain, Spectrin alpha chain brain, Spectrin alpha non erythrocytic 1, Spectrin non erythroid alpha chain, Spectrin, alpha, non-erythrocytic 1 alpha-fodrin, Spectrin, nonerythroid, alpha subunit, Spna2, SPTA 2, SPTA2, SPTAN 1, SPTAN1, SPTA1_HUMAN.

Background: a-Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.

Gen-ID: 5795

Pathways: Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization