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SPTAN1 Antikörper (AA 2351-2475)

SPTAN1 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal SPTAN1-3351 unconjugated
Produktnummer ABIN6940647
  • Target Alle SPTAN1 Antikörper anzeigen
    SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
    Bindungsspezifität
    • 15
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2351-2475
    Reaktivität
    • 77
    • 40
    • 40
    • 22
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 101
    • 16
    • 1
    Maus
    Klonalität
    • 92
    • 26
    Monoklonal
    Konjugat
    • 60
    • 21
    • 13
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPTAN1 Antikörper ist unkonjugiert
    Applikation
    • 83
    • 45
    • 21
    • 20
    • 16
    • 14
    • 14
    • 11
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment of human SPTAN1 protein (around aa 2351-2475) (exact sequence is proprietary)
    Klon
    SPTAN1-3351
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product SPTAN1 Primärantikörper
  • Applikationshinweise

    Positive Control: Human colon or kidney tissues (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
    Andere Bezeichnung
    SPTAN1 (SPTAN1 Produkte)
    Synonyme
    im:7157190 antikoerper, wu:fa20e05 antikoerper, wu:fb33g08 antikoerper, wu:fk32a10 antikoerper, zgc:112229 antikoerper, 2610027H02Rik antikoerper, Spna-2 antikoerper, Spna2 antikoerper, EIEE5 antikoerper, NEAS antikoerper, SPTA2 antikoerper, A2a antikoerper, IPF antikoerper, SPECA antikoerper, spectrin alpha, non-erythrocytic 1 antikoerper, spectrin, alpha, non-erythrocytic 1 antikoerper, SPTAN1 antikoerper, sptan1 antikoerper, Sptan1 antikoerper
    Hintergrund
    Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous and chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin I and spectrin I are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin II (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin II, a neuronal cytoskeleton protein.
    Molekulargewicht
    240kDa
    Gen-ID
    6709
    UniProt
    Q13813
    Pathways
    Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization
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