Diazepam Binding Inhibitor Antikörper (AA 2-87) (Cy3)

Produktnummer ABIN7985135

Der Cy3-konjugierte Kaninchen Polyklonal anti-Diazepam Binding Inhibitor Antikörper (ABIN7985135) detektiert spezifisch Diazepam Binding Inhibitor in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Diazepam Binding Inhibitor Antikörper (AA 2-87) (Cy3) (ABIN7985135)

Target: Diazepam Binding Inhibitor (DBI)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Diazepam Binding Inhibitor Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Diazepam Binding Inhibitor Antikörper (Cy3)

Bindungsspezifität: AA 2-87

Verwendungszweck: Anti-Diazepam Binding Inhibitor/DBI Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: coli-derived human DBI recombinant protein (Position: S2-I87). Human DBI shares 77.9% amino acid (aa) sequence identity with both mouse,rat DBI.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human DBI recombinant protein (Position: S2-I87). Human DBI shares 77.9% amino acid (aa) sequence identity with both mouse and rat DBI.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Diazepam Binding Inhibitor

Target: Diazepam Binding Inhibitor (DBI)

Andere Bezeichnung: DBI

Hintergrund:

Background: Acyl-CoA-binding protein is a protein that in humans is encoded by the DBI gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: diazepam binding inhibitor, acyl-CoA binding protein

Gen-ID: 1622

UniProt: P07108