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Diazepam Binding Inhibitor Antikörper (AA 1-114)

DBI Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6139420
  • Target Alle Diazepam Binding Inhibitor (DBI) Antikörper anzeigen
    Diazepam Binding Inhibitor (DBI)
    Bindungsspezifität
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-114
    Reaktivität
    • 34
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 2
    Kaninchen
    Klonalität
    • 38
    • 1
    Polyklonal
    Konjugat
    • 20
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Diazepam Binding Inhibitor Antikörper ist unkonjugiert
    Applikation
    • 28
    • 16
    • 16
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    MWGDLWLLPP ASANPGTGTE AEFEKAAEEV RHLKTKPSDE EMLFIYGHYK QATVGDINTE RPGMLDFTGK AKWDAWNELK GTSKEDAMKA YINKVEELKK KYGI
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human DBI (NP_001171513.1).
    Isotyp
    IgG
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  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Diazepam Binding Inhibitor (DBI)
    Andere Bezeichnung
    DBI (DBI Produkte)
    Synonyme
    ACBD1 antikoerper, ACBP antikoerper, CCK-RP antikoerper, EP antikoerper, dbib antikoerper, DBI antikoerper, wu:fb63e10 antikoerper, zgc:56108 antikoerper, zgc:77734 antikoerper, Acbp antikoerper, endozepine antikoerper, Acoabp3 antikoerper, Ep antikoerper, Odn antikoerper, RNACOABP3 antikoerper, Ttn antikoerper, acbd1 antikoerper, acbp antikoerper, cck-rp antikoerper, dbi antikoerper, dbi-a antikoerper, dbi-b antikoerper, dbia antikoerper, diazepam binding inhibitor, acyl-CoA binding protein antikoerper, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) S homeolog antikoerper, diazepam-binding inhibitor antikoerper, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) antikoerper, acyl-CoA-binding protein antikoerper, diazepam binding inhibitor antikoerper, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) L homeolog antikoerper, DBI antikoerper, dbi.S antikoerper, dbi antikoerper, LOC706367 antikoerper, Dbi antikoerper, dbi.L antikoerper
    Hintergrund
    This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.,DBI,ACBD1,ACBP,CCK-RP,EP,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,DBI
    Molekulargewicht
    10 kDa/11 kDa/13 kDa/14 kDa/16 kDa
    Gen-ID
    1622
    UniProt
    P07108
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