DOCK1 Antikörper (AA 100-1732) (Biotin)

Produktnummer ABIN7984570

Der Kaninchen Polyklonal anti-DOCK1 Antikörper wird verwendet zum Nachweis von DOCK1 in Proben von Human. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für DOCK1 Antikörper (AA 100-1732) (Biotin) (ABIN7984570)

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-DOCK1 Antikörper (Biotin)

Bindungsspezifität: AA 100-1732

Verwendungszweck: Anti-DOCK180/DOCK1 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DOCK180/DOCK1 recombinant protein (Position: S100-T1732).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DOCK1

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Andere Bezeichnung: DOCK1

Hintergrund:

Background: Dock180, (Dedicator of cytokinesis) also known as DOCK1, is a large (~180 kDa) protein involved in intracellular signalling networks. This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Gene Full Name: dedicator of cytokinesis 1

Gen-ID: 1793

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor