DOCK1 Antikörper (AA 1630-1710)

Produktnummer ABIN7220068

Der Kaninchen Polyklonal anti-DOCK1 Antikörper (ABIN7220068) detektiert spezifisch DOCK1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für DOCK1 Antikörper (AA 1630-1710) (ABIN7220068)

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DOCK1 Antikörper

Bindungsspezifität: AA 1630-1710

Verwendungszweck: Rabbit Anti-DOCK 180 Polyclonal Antibody

Spezifität: DOCK 180 Polyclonal Antibody detects endogenous levels of DOCK 180 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human DOCK 180 at AA range: 1630-1710

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DOCK1

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Andere Bezeichnung: DOCK 180

Hintergrund: DOCK1, Dedicator of cytokinesis protein 1, 180 kDa protein downstream of CRK, DOCK180DOCK1 encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. Dedicator of cytokinesis protein 1 regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 215kD

Gen-ID: 1793

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor