CYLD Antikörper (AA 618-956)

Produktnummer ABIN7982582

Der Kaninchen Polyklonal anti-CYLD Antikörper (ABIN7982582) detektiert spezifisch CYLD in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.

Kurzübersicht für CYLD Antikörper (AA 618-956) (ABIN7982582)

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYLD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Güteklasse: Carrier-free

Produktdetails anti-CYLD Antikörper

Bindungsspezifität: AA 618-956

Verwendungszweck: Anti-CYLD Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human CYLD shares 97.6%,97.9% amino acid (aa) sequence identity with mouse,rat CYLD,respectively.

Produktmerkmale: Anti-CYLD Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CYLD recombinant protein (Position: D618-K956). Human CYLD shares 97.6% and 97.9% amino acid (aa) sequence identity with mouse and rat CYLD, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CYLD

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Andere Bezeichnung: CYLD

Hintergrund:

Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Full Name: CYLD lysine 63 deubiquitinase

Sequence Similarities: Belongs to the peptidase C19 family.

Molekulargewicht: 107 kDa

Gen-ID: 1540

UniProt: Q9NQC7

Pathways: Apoptose, Activation of Innate immune Response