CYLD Antikörper (AA 618-956) (HRP)

Produktnummer ABIN7982578

Der Kaninchen Polyklonal anti-CYLD Antikörper wird verwendet zum Nachweis von CYLD in Proben von Human und Ratte. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für CYLD Antikörper (AA 618-956) (HRP) (ABIN7982578)

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYLD Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CYLD Antikörper (HRP)

Bindungsspezifität: AA 618-956

Verwendungszweck: Anti-CYLD Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human CYLD shares 97.6%,97.9% amino acid (aa) sequence identity with mouse,rat CYLD,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CYLD recombinant protein (Position: D618-K956). Human CYLD shares 97.6% and 97.9% amino acid (aa) sequence identity with mouse and rat CYLD, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CYLD

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Andere Bezeichnung: CYLD

Hintergrund:

Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Full Name: CYLD lysine 63 deubiquitinase

Sequence Similarities: Belongs to the peptidase C19 family.

Gen-ID: 1540

UniProt: Q9NQC7

Pathways: Apoptose, Activation of Innate immune Response