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Cyclin B1 Antikörper (AA 1-433) (PE)

Der PE-konjugierte Kaninchen Polyklonal anti-Cyclin B1 Antikörper (ABIN7982129) detektiert spezifisch Cyclin B1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Produktnummer ABIN7982129
995,50 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 8 bis 12 Werktagen

Kurzübersicht für Cyclin B1 Antikörper (AA 1-433) (PE) (ABIN7982129)

Target

Alle Cyclin B1 (CCNB1) Antikörper anzeigen
Cyclin B1 (CCNB1)

Reaktivität

  • 264
  • 115
  • 58
  • 24
  • 21
  • 16
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 226
  • 44
Kaninchen

Klonalität

  • 168
  • 102
Polyklonal

Konjugat

  • 124
  • 14
  • 8
  • 8
  • 7
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
Dieser Cyclin B1 Antikörper ist konjugiert mit PE

Applikation

  • 176
  • 106
  • 82
  • 77
  • 65
  • 43
  • 40
  • 39
  • 35
  • 33
  • 9
  • 9
  • 8
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • Bindungsspezifität

    • 39
    • 22
    • 16
    • 16
    • 13
    • 12
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-433

    Verwendungszweck

    Anti-Cyclin B1/CCNB1 Antibody PE Conjugated

    Spezifität

    No cross reactivity with other proteins.

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Homologie

    Human Cyclin B1 shares 86%,85% amino acid (aa) sequences identity with mouse,rat Cyclin B1,respectively.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Cyclin B1 recombinant protein (Position: M1-V433). Human Cyclin B1 shares 86% and 85% amino acid (aa) sequences identity with mouse and rat Cyclin B1, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Flow Cytometry, Optimal dilutions should be determined by end users.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    Haltbarkeit

    12 months
  • Target

    Cyclin B1 (CCNB1)

    Andere Bezeichnung

    CCNB

    Hintergrund

    Background: CCNB also known as Cyclin B1, is a protein that in humans is encoded by the CCNB1 gene, and it is mapped to 5q13.2. The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. CCNB contributes to the switch-like all or none behavior of the cell in deciding to commit to mitosis. Its activation is well-regulated, and positive feedback loops ensure that once the cyclin B1-Cdk1 complex is activated, it is not deactivated.

    Gene Full Name: cyclin B1

    Sequence Similarities: Belongs to the cyclin family. Cyclin AB subfamily.

    Gen-ID

    891

    UniProt

    P14635

    Pathways

    Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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