Prothrombin Antikörper (AA 97-124) (Cy3)

Produktnummer ABIN7980688

Der Maus Monoklonal anti-Prothrombin Antikörper wird verwendet zum Nachweis von Prothrombin in Proben von Human, Ratte und Maus. Er wurde validiert für FACS.

Kurzübersicht für Prothrombin Antikörper (AA 97-124) (Cy3) (ABIN7980688)

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prothrombin Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Klon: 5B6G1

Produktdetails anti-Prothrombin Antikörper (Cy3)

Bindungsspezifität: AA 97-124

Verwendungszweck: Anti-Prothrombin Antibody (monoclonal, 5B6G1) Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Prothrombin recombinant protein (Position: Y97-R124).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Prothrombin

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Andere Bezeichnung: F2

Hintergrund:

Background: F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. This gene for human prothrombin (F2) was assigned to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.

Gene Full Name: coagulation factor II, thrombin

Gen-ID: 2147

UniProt: P00734

Pathways: Komplementsystem, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling