CXCR1 Antikörper (N-Term) (HRP)

Produktnummer ABIN7979251

Der Kaninchen Polyklonal anti-CXCR1 Antikörper wird verwendet zum Nachweis von CXCR1 in Proben von Human. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für CXCR1 Antikörper (N-Term) (HRP) (ABIN7979251)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CXCR1 Antikörper (HRP)

Bindungsspezifität: N-Term

Verwendungszweck: Anti-CXCR1 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Andere Bezeichnung: CXCR1

Hintergrund:

Background: CXCR1 (Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al. (1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al. (2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Gene Full Name: C-X-C motif chemokine receptor 1

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

Gen-ID: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process