CXCR1 Antikörper (AA 250-350)
Kurzübersicht für CXCR1 Antikörper (AA 250-350) (ABIN7266317)
Target
Alle CXCR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 250-350
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Verwendungszweck
- CXCR1 Rabbit pAb
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Sequenz
- IFLLCWLPYN LVLLADTLMR TQVIQESCER RNNIGRALDA TEILGFLHSC LNPIIYAFIG QNFRHGFLKI LAMHGLVSKE FLARHRVTSY TSSSVNVSSN L
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CXCR1 (NP_000625.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
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Andere Bezeichnung
- CXCR1
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Hintergrund
- The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.,CXCR1,C-C,C-C-CKR-1,CD128,CD181,CDw128a,CKR-1,CMKAR1,IL8R1,IL8RA,IL8RBA,Cancer,Tumor immunology,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,CXCR1
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Molekulargewicht
- 39kDa
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Gen-ID
- 3577
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UniProt
- P25024
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Pathways
- cAMP Metabolic Process
Target
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