CXCR1 Antikörper
Kurzübersicht für CXCR1 Antikörper (ABIN7073465)
Target
Alle CXCR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse CXCR1
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Applikationshinweise
- WB (H,M,R) 1: 500-1: 1000, IHC/IF (H,M,R) 1:1000-1:4000/1:500-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
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Andere Bezeichnung
- CXCR1
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Hintergrund
- CXCR1 is a chemokine receptor, which is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein-activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. Stimulation of CXCR1 in neutrophils by its primary ligand, Interleukin 8, leads to neutrophil chemotaxis and activation.
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Molekulargewicht
- 45 kDa
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Gen-ID
- 227288
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NCBI Accession
- NP_839972
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UniProt
- Q810W6
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Pathways
- cAMP Metabolic Process
Target
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