CENPE Antikörper (AA 1390-2474) (Fluoro550)

Produktnummer ABIN7978059

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CENPE in FACS. Es zeigt Reaktivität gegenüber Proben von Ratte und Maus.

Kurzübersicht für CENPE Antikörper (AA 1390-2474) (Fluoro550) (ABIN7978059)

Target: CENPE (Centromere Protein E, 312kDa (CENPE))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPE Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CENPE Antikörper (Fluoro550)

Bindungsspezifität: AA 1390-2474

Verwendungszweck: Anti-Cenpe Antibody Fluoro550 Conjugated

Homologie: Mouse Cenpe shares 49.9% amino acid (aa) sequence identity with human Cenpe,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Cenpe recombinant protein (Position: Q1390-Q2474). Mouse Cenpe shares 49.9% amino acid (aa) sequence identity with human Cenpe, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CENPE

Target: CENPE (Centromere Protein E, 312kDa (CENPE))

Andere Bezeichnung: Cenpe

Hintergrund:

Background: Centromere-associated protein E is a protein that in humans is encoded by the CENPE gene. Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.

Gene Full Name: centromere protein E

Gen-ID: 229841

UniProt: Q6RT24

Pathways: M Phase, Maintenance of Protein Location