CENPE Antikörper (AA 2542-2701)
Kurzübersicht für CENPE Antikörper (AA 2542-2701) (ABIN7266274)
Target
Alle CENPE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 2542-2701
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Verwendungszweck
- CENPE Rabbit pAb
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Sequenz
- ALILKSEHIR LEKEISKLKQ QNEQLIKQKN ELLSNNQHLS NEVKTWKERT LKREAHKQVT CENSPKSPKV TGTASKKKQI TPSQCKERNL QDPVPKESPK SCFFDSRSKS LPSPHPVRYF DNSSLGLCPE VQNAGAESVD SQPGPWHASS GKDVPECKTQ
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 2542-2701 of human CENPE (NP_001804.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:200 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CENPE (Centromere Protein E, 312kDa (CENPE))
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Andere Bezeichnung
- CENPE
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Hintergrund
- Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.,CENPE,CENP-E,KIF10,MCPH13,PPP1R61,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centromere,CENPE
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Molekulargewicht
- 301kDa/312kDa/316kDa
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Gen-ID
- 1062
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UniProt
- Q02224
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Pathways
- M Phase, Maintenance of Protein Location
Target
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