CD70 Antikörper (AA 36-191) (Fluoro647)

Produktnummer ABIN7977349

Der Kaninchen Polyklonal anti-CD70 Antikörper wird verwendet zum Nachweis von CD70 in Proben von Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für CD70 Antikörper (AA 36-191) (Fluoro647) (ABIN7977349)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD70 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CD70 Antikörper (Fluoro647)

Bindungsspezifität: AA 36-191

Verwendungszweck: Anti-Cd70 Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Cd70 recombinant protein (Position: C36-Q191).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: Cd70

Hintergrund:

Background: CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Gene Full Name: CD70 antigen

Gen-ID: 21948

UniProt: O55237

Pathways: Cancer Immune Checkpoints