Rekombinanter CD70 Antikörper (AA 50-193)
Kurzübersicht für Rekombinanter CD70 Antikörper (AA 50-193) (ABIN7795663)
Target
Alle CD70 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 50-193
-
Verwendungszweck
- Rabbit anti-CD70 Recombinant Monoclonal Antibody [BLR266L]
-
Aufreinigung
- Purified
-
Immunogen
- Residues 50-193 (ECD)
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 500 μg/mL
-
Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- 2 - 8 °C
-
Haltbarkeit
- 12 months
-
-
- CD70 (CD70 Molecule (CD70))
-
Andere Bezeichnung
- CD70
-
Hintergrund
- CD70, a cytokine that belongs to the tumor necrosis factor (TNF) ligand family, is a ligand for TNFRSF27/CD27. CD70 is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. CD70 also plays a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. [taken from NCBI Entrez Gene (Gene ID: 970)].
-
Gen-ID
- 970
-
UniProt
- P32970
-
Pathways
- Cancer Immune Checkpoints
Target
-