Caspase 2 Antikörper (AA 170-325) (HRP)
Kurzübersicht für Caspase 2 Antikörper (AA 170-325) (HRP) (ABIN7975234)
Target
Alle Caspase 2 (CASP2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 170-325
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Verwendungszweck
- Anti-Caspase-2/CASP2 Antibody HRP Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E. coli-derived human Caspase-2 recombinant protein (Position: G170-T325).
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Isotyp
- IgG
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Applikationshinweise
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
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Andere Bezeichnung
- CASP2
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Hintergrund
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Background: Caspase-2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. activation of caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli. Caspase-2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.
Gene Full Name: caspase 2
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Gen-ID
- 835
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UniProt
- P42575
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Neurotrophin Signalübertragung
Target
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