Bestrophin 1 Antikörper (AA 9-551) (PE)

Produktnummer ABIN7972605

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Bestrophin 1 in FACS. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für Bestrophin 1 Antikörper (AA 9-551) (PE) (ABIN7972605)

Target: Bestrophin 1 (BEST1)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bestrophin 1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Bestrophin 1 Antikörper (PE)

Bindungsspezifität: AA 9-551

Verwendungszweck: Anti-Bestrophin-1/Best1 Antibody PE Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Mouse Best1 shares 64.3% amino acid (aa) sequence identity with human Best1.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Bestrophin-1/Best1 recombinant protein (Position: V9-E551). Mouse Best1 shares 64.3% amino acid (aa) sequence identity with human Best1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Bestrophin 1

Target: Bestrophin 1 (BEST1)

Andere Bezeichnung: Best1

Hintergrund:

Background: Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Gene Full Name: bestrophin 1

Gen-ID: 24115

UniProt: O88870