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Id2 Antikörper (AA 31-134) (Biotin)

Dieses Rabbit Polyclonal-Antikörper erkennt spezifisch Id2 in ELISA, IHC (p), IHC (fro). Er zeigt eine Reaktivität gegenüber Rat.
Produktnummer ABIN747475

Kurzübersicht für Id2 Antikörper (AA 31-134) (Biotin) (ABIN747475)

Target

Alle Id2 Antikörper anzeigen
Id2 (Inhibitor of DNA Binding 2 (Id2))

Reaktivität

  • 35
  • 31
  • 15
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Ratte

Wirt

  • 40
  • 9
  • 1
Kaninchen

Klonalität

  • 42
  • 8
Polyklonal

Konjugat

  • 24
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Id2 Antikörper ist konjugiert mit Biotin

Applikation

  • 22
  • 19
  • 13
  • 13
  • 9
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-134

    Spezifität

    Due to the similarity of this protein with ID1, this antibody has a chance to have light cross-reactivity with ID1 due to a 77 % sequence similarity in the range of our immunogen.

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human GIG8/ID2

    Isotyp

    IgG
  • Applikationshinweise

    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    Id2 (Inhibitor of DNA Binding 2 (Id2))

    Andere Bezeichnung

    ID2

    Hintergrund

    Synonyms: GIG8, ID2A, ID2H, bHLHb26, DNA-binding protein inhibitor ID-2, Class B basic helix-loop-helix protein 26, Inhibitor of DNA binding 2, Inhibitor of differentiation 2, ID2

    Background: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.

    Gen-ID

    3398

    UniProt

    Q02363
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