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Id2 Antikörper (AA 31-134)

Id2 Reaktivität: Ratte ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN747473
  • Target Alle Id2 Antikörper anzeigen
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    Bindungsspezifität
    • 14
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-134
    Reaktivität
    • 31
    • 30
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 40
    • 5
    • 1
    Kaninchen
    Klonalität
    • 42
    • 4
    Polyklonal
    Konjugat
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Id2 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 17
    • 12
    • 12
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    Due to the similarity of this protein with ID1, this antibody has a chance to have light cross-reactivity with ID1 due to a 77 % sequence similarity in the range of our immunogen.
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GIG8/ID2
    Isotyp
    IgG
    Top Product
    Discover our top product Id2 Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    Andere Bezeichnung
    ID2 (Id2 Produkte)
    Synonyme
    AI255428 antikoerper, C78922 antikoerper, Idb2 antikoerper, bHLHb26 antikoerper, Ac2-300 antikoerper, GIG8 antikoerper, ID2A antikoerper, ID2H antikoerper, XId2 antikoerper, id2-A antikoerper, inhibitor of DNA binding 2 antikoerper, inhibitor of DNA binding 2, HLH protein antikoerper, inhibitor of DNA binding 2 L homeolog antikoerper, Id2 antikoerper, ID2 antikoerper, id2.L antikoerper
    Hintergrund

    Synonyms: GIG8, ID2A, ID2H, bHLHb26, DNA-binding protein inhibitor ID-2, Class B basic helix-loop-helix protein 26, Inhibitor of DNA binding 2, Inhibitor of differentiation 2, ID2

    Background: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.

    Gen-ID
    3398
    UniProt
    Q02363
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