APOA1 Antikörper (AA 25-264)

Produktnummer ABIN7969289

Der Kaninchen Polyklonal anti-APOA1 Antikörper (ABIN7969289) detektiert spezifisch APOA1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für APOA1 Antikörper (AA 25-264) (ABIN7969289)

Target: APOA1 (Apolipoprotein A-I (APOA1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Güteklasse: Carrier-free

Produktdetails anti-APOA1 Antikörper

Bindungsspezifität: AA 25-264

Verwendungszweck: Anti-Apolipoprotein A I/APOA1 Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: coli-derived mouse APOA1 recombinant protein (Position: D25-Q264). Mouse APOA1 shares 64%,68.6% amino acid (aa) sequence identity with human,rat APOA1,respectively.

Produktmerkmale: Anti-Apolipoprotein A I/APOA1 Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse APOA1 recombinant protein (Position: D25-Q264). Mouse APOA1 shares 64% and 68.6% amino acid (aa) sequence identity with human and rat APOA1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse Western blot, 0.1-0.5 μg/mL, Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu APOA1

Target: APOA1 (Apolipoprotein A-I (APOA1))

Andere Bezeichnung: Apoa1

Hintergrund:

Background: Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.

Gene Full Name: apolipoprotein A-I

Molekulargewicht: 25 kDa

Gen-ID: 11806

UniProt: Q00623

Pathways: Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism