APC2 Antikörper (N-Term) (PE)

Produktnummer ABIN7969232

Der PE-konjugierte Kaninchen Polyklonal anti-APC2 Antikörper (ABIN7969232) detektiert spezifisch APC2 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für APC2 Antikörper (N-Term) (PE) (ABIN7969232)

Target: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APC2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-APC2 Antikörper (PE)

Bindungsspezifität: N-Term

Verwendungszweck: Anti-APC2 Antibody PE Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by two amino acids.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human APC2, different from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu APC2

Target: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Andere Bezeichnung: APC2

Hintergrund:

Background: APC2, which is also called APCL, is a deduced 2,303-amino acid protein that contains an N-terminal coiled-coil domain, followed by an armadillo domain and five 20-amino acid repeats. The human APC2 gene is mapped to chromosome 19p13.3. It is found that the 20-amino acid repeat domain of APCL could bind beta-catenin (CTNNB1) and deplete the intracellular beta-catenin pool. A reporter gene assay revealed that APCL could regulate interaction of beta-catenin with T cell-specific transcription factors (TCF7), although less efficiently than APC.

Gene Full Name: APC regulator of Wnt signaling pathway 2

Gen-ID: 10297

UniProt: O95996

Pathways: WNT Signalweg