ANAPC5 Antikörper (AA 1-266) (Fluoro550)

Produktnummer ABIN7968369

Der Fluoro550-konjugierte Kaninchen Polyklonal anti-ANAPC5 Antikörper (ABIN7968369) detektiert spezifisch ANAPC5 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ANAPC5 Antikörper (AA 1-266) (Fluoro550) (ABIN7968369)

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC5 Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ANAPC5 Antikörper (Fluoro550)

Bindungsspezifität: AA 1-266

Verwendungszweck: Anti-Apc5/ANAPC5 Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Apc5/ANAPC5 recombinant protein (Position: M1-D266).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ANAPC5

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Andere Bezeichnung: ANAPC5

Hintergrund:

Background: Anaphase-promoting complex subunit 5 is an enzyme that in humans is encoded by the ANAPC5 gene. This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

Gene Full Name: anaphase promoting complex subunit 5

Gen-ID: 51433

UniProt: Q9UJX4

Pathways: M Phase