ANAPC5 Antikörper (AA 156-185)

Produktnummer ABIN654927

Der Kaninchen Polyklonal anti-ANAPC5 Antikörper (Klon RB24572) (ABIN654927) detektiert spezifisch ANAPC5 in WB und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ANAPC5 Antikörper (AA 156-185) (ABIN654927)

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB24572

Produktdetails anti-ANAPC5 Antikörper

Bindungsspezifität: AA 156-185

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ANAPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ANAPC5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ANAPC5

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Andere Bezeichnung: ANAPC5

Hintergrund: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

Molekulargewicht: 85077

Gen-ID: 51433

NCBI Accession: NP_001131031, NP_057321

UniProt: Q9UJX4

Pathways: M Phase