MAPT Antikörper (pSer739)
Kurzübersicht für MAPT Antikörper (pSer739) (ABIN747098)
Target
Alle MAPT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer739
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Verwendungszweck
- phospho-Tau (Ser422) Polyclonal Antibody
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Spezifität
- This phosphorylation site is homologous to that of Ser714 in Mouse and Ser733 in Rat.
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Dog,Cow,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser739 [VD(p-S)PQ]
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Isotyp
- IgG
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anti-Microtubule-Associated Protein tau (MAPT) (AA 1-100) antibody
MAPT Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 34-368) antibodyMAPT Reaktivität: Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 130-386) antibodyMAPT Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer396) antibodyMAPT Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibodyMAPT Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer396) antibodyMAPT Reaktivität: Human WB, IHC (p), IHC (fro), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 677-707), (C-Term) antibodyMAPT Reaktivität: Human, Ratte, Maus, Cynomolgus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB2883 unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 677-707) antibodyMAPT Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer202), (pThr205) antibodyMAPT Reaktivität: Human WB, ELISA, IHC, IF, ICC, DB Wirt: Kaninchen Monoclonal AH36 unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer202), (pThr205) antibody (Atto 488)MAPT Reaktivität: Human WB, ELISA, IHC, IF, ICC, DB Wirt: Kaninchen Monoclonal AH36 Atto 488
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Applikationshinweise
- WB(1:300-5000),
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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Andere Bezeichnung
- Tau protein
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Hintergrund
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Synonyms: TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R103, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT
Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Gen-ID
- 4137
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UniProt
- P10636
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Pathways
- MAPK Signalweg, Microtubule Dynamics, M Phase, Regulation of Cell Size
Target
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