ADAM8 Antikörper (AA 41-290) (Biotin)

Produktnummer ABIN7966364

Der Kaninchen Polyklonal anti-ADAM8 Antikörper wird verwendet zum Nachweis von ADAM8 in Proben von Human und Ratte. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für ADAM8 Antikörper (AA 41-290) (Biotin) (ABIN7966364)

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAM8 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ADAM8 Antikörper (Biotin)

Bindungsspezifität: AA 41-290

Verwendungszweck: Anti-MS2/ADAM8 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MS2/ADAM8 recombinant protein (Position: R41-L290).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ADAM8

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Andere Bezeichnung: ADAM8

Hintergrund:

Background: A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

Gene Full Name: ADAM metallopeptidase domain 8

Gen-ID: 101

UniProt: P78325

Pathways: Activation of Innate immune Response, M Phase