Rekombinanter MSH3 Antikörper

Produktnummer ABIN7938356

Der Kaninchen Monoklonal anti-MSH3 Antikörper wird verwendet zum Nachweis von MSH3 in Proben von Human und Ratte. Er wurde validiert für WB.

Kurzübersicht für Rekombinanter MSH3 Antikörper (ABIN7938356)

Target: MSH3 (MutS Homolog 3 (MSH3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MSH3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1J23

Produktdetails anti-MSH3 Antikörper

Verwendungszweck: MSH3 antibody (rAb), 100 μg (Clone 1J23)

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against the MSH3 fusion protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:10000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu MSH3

Target: MSH3 (MutS Homolog 3 (MSH3))

Andere Bezeichnung: MSH3

Hintergrund:

Background_Plain: MSH3 is a DNA mismatch repair (MMR) gene that heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. It undergoes frequent somatic mutation in colorectal cancers (CRCs) with MMR deficiency. MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.

Aliases: MutS Homolog 3, FAP4

Molekulargewicht: 127 kDa

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response