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MSH3 Antikörper (N-Term)

MSH3 Reaktivität: Human, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6263385
  • Target Alle MSH3 Antikörper anzeigen
    MSH3 (MutS Homolog 3 (MSH3))
    Bindungsspezifität
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 29
    • 2
    • 2
    Human, Ratte
    Wirt
    • 28
    • 1
    Kaninchen
    Klonalität
    • 27
    • 2
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MSH3 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 13
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    MSH3 Antibody detects endogenous levels of total MSH3.
    Homologie
    Pig,Horse,Sheep,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MSH3, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product MSH3 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    MSH3 (MutS Homolog 3 (MSH3))
    Andere Bezeichnung
    MSH3 (MSH3 Produkte)
    Synonyme
    ATMSH3 antikoerper, M7J2.90 antikoerper, M7J2_90 antikoerper, homolog of DNA mismatch repair protein MSH3 antikoerper, DUP antikoerper, MRP1 antikoerper, D13Em1 antikoerper, Rep-3 antikoerper, Rep3 antikoerper, mutS homolog 3 antikoerper, DNA mismatch repair protein MSH3 antikoerper, homolog of DNA mismatch repair protein MSH3 antikoerper, mismatch repair protein antikoerper, MSH3 antikoerper, Msh3 antikoerper
    Hintergrund

    Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

    Gene: MSH3

    Molekulargewicht
    127kDa
    Gen-ID
    4437
    UniProt
    P20585
    Pathways
    DNA Reparatur, Production of Molecular Mediator of Immune Response
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