N6-Methyladenosine Antikörper

Produktnummer ABIN7938031

Dieser Maus Monoklonal Antikörper detektiert spezifisch N6-Methyladenosine in DB und IP. Es zeigt Reaktivität gegenüber Proben von Human und Saccharomyces cerevisiae.

Kurzübersicht für N6-Methyladenosine Antikörper (ABIN7938031)

Target: N6-Methyladenosine

Reaktivität: Human, Saccharomyces cerevisiae

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Dot Blot (DB), Immunoprecipitation (IP)

Klon: 17-3-4-1

Produktdetails

Verwendungszweck: N6-Methyladenosine (m6A) antibody (mAb) (Clone 17-3-4-1), sample

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against 6-Methyladenosine conjugated to BSA.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: For N6-Methyladenosine (m6A), we also offer an AbFlex N6-Methyladenosine (m6A) Recombinant Antibody (rAb). For details, see Catalog No. 91261.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Antigendetails

Target: N6-Methyladenosine

Substanzklasse: Chemical

Hintergrund: N6-Methyladenosine (m6A) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well.