N6-Methyladenosine Antikörper

Produktnummer ABIN2668972

Der Kaninchen Polyklonal anti-N6-Methyladenosine Antikörper wird verwendet zum Nachweis von N6-Methyladenosine. Er wurde validiert für DB.

Kurzübersicht für N6-Methyladenosine Antikörper (ABIN2668972)

Target: N6-Methyladenosine

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Dot Blot (DB)

Produktdetails

Verwendungszweck: N6-Methyladenosine (m6A) antibody (pAb)

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against 6-Methyladenosine conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DB: 1 - 2 μg/mL dilution For N6-Methyladenosine (m6A), we also offer AbFlex N6-Methyladenosine (m6A) Recombinant Antibody (rAb). For details, see Catalog No. 91261.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Antigendetails

Target: N6-Methyladenosine

Substanzklasse: Chemical

Hintergrund: N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well.