N6-Methyladenosine Antikörper

Produktnummer ABIN6972397

Produktdetails

Target: N6-Methyladenosine

Reaktivität: Human, Saccharomyces cerevisiae

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Dot Blot (DB), Immunoprecipitation (IP)

Produktmerkmale: N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well. N6-Methyladenosine (m6A) antibody (mAb) (Clone 17-3-4-1) was raised in a Mouse host. It has been validated for use in Dot blot and Immunoprecipitation, it has been shown to react with Budding Yeast and Human samples, but the sequence is not species specific so it should react with a wide range of sample types.

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against 6-Methyladenosine conjugated to BSA.

Klon: 17-3-4-1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Antigendetails

Target: N6-Methyladenosine

Andere Bezeichnung: N6-Methyladenosine (m6A)