TSHB Antikörper

Produktnummer ABIN7882485

Dieser Maus Monoklonal Antikörper detektiert spezifisch TSHB in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TSHB Antikörper (ABIN7882485)

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TSHB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: TSHb-1317

Produktdetails anti-TSHB Antikörper

Verwendungszweck: TSHB Antibody / TSH beta (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein was used as the immunogen for this TSHB antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TSHB antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the TSHB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu TSHB

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Andere Bezeichnung: TSHB

Hintergrund: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

UniProt: P01222

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism