Rekombinanter TSHB Antikörper

Produktnummer ABIN7882484

Der Kaninchen Monoklonal anti-TSHB Antikörper (Klon TSHb-7001R) (ABIN7882484) detektiert spezifisch TSHB in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter TSHB Antikörper (ABIN7882484)

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TSHB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: TSHb-7001R

Produktdetails anti-TSHB Antikörper

Verwendungszweck: Recombinant TSH beta Antibody / TSHB

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant human TSH beta protein fragment was used as the immunogen for the recombinant TSH beta antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant TSH beta antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant TSH beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu TSHB

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Andere Bezeichnung: TSH beta

Hintergrund: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

UniProt: P01222

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism