Rekombinanter TSHB Antikörper

Produktnummer ABIN7882483

Der Kaninchen Monoklonal anti-TSHB Antikörper wird verwendet zum Nachweis von TSHB in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter TSHB Antikörper (ABIN7882483)

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TSHB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: TSHb-7001R

Produktdetails anti-TSHB Antikörper

Verwendungszweck: Recombinant TSH beta Antibody / TSHB (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant human TSH beta protein fragment was used as the immunogen for the recombinant TSH beta antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant TSH beta antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant TSH beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu TSHB

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Andere Bezeichnung: TSH beta

Hintergrund: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

UniProt: P01222

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism