Der Kaninchen Monoklonal anti-RPS6KA3 Antikörper (Klon 28R24) (ABIN7882175) detektiert spezifisch RPS6KA3 in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
RPS6KA3
Reaktivität: Human
IHC, IF (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal dilution of the RSK2 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store the RSK2 antibody at -20oC.
Target
RPS6KA3
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
Andere Bezeichnung
RSK2
Hintergrund
Ribosomal protein S6 kinase alpha 3 (RPS6KA3, RSK2) is a serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. [UniProt]