Retinoblastoma Protein (Rb) Antikörper

Produktnummer ABIN7882157

Der Kaninchen Monoklonal anti-Retinoblastoma Protein (Rb) Antikörper (Klon BHC-18) (ABIN7882157) detektiert spezifisch Retinoblastoma Protein (Rb) in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Retinoblastoma Protein (Rb) Antikörper (ABIN7882157)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: BHC-18

Produktdetails anti-Retinoblastoma Protein (Rb) Antikörper

Verwendungszweck: Retinoblastoma Antibody / Rb1

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human Retinoblastoma / Rb was used as the immunogen for the Retinoblastoma antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Retinoblastoma antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the Retinoblastoma antibody at -20oC.

Details zu Retinoblastoma Protein (Rb)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Andere Bezeichnung: Retinoblastoma

Hintergrund: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [RefSeq]

UniProt: P06400

Pathways: Mitotic G1-G1/S Phases